Laboratory Results and Clinical Characteristics of Probable Omicron Patients at Dr. Wahidin Sudirohusodo Hospital

Fadhlan Fadhlan; Uleng Bahrun; Tenri Esa

doi:10.24293/ijcpml.v30i2.2108

Authors

Fadhlan Fadhlan Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo, Makassar
Uleng Bahrun Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo, Makassar; Hasanuddin University Hospital, Makassar
Tenri Esa Department of Clinical Pathology, Faculty of Medicine, Hasanuddin University/Dr. Wahidin Sudirohusodo, Makassar; Clinical Pathology Laboratory, Dadi Special Provincial Hospital of South Sulawesi, Makassar

DOI:

https://doi.org/10.24293/ijcpml.v30i2.2108

Keywords:

COVID-19, probable Omicron, characteristics

Abstract

Since the Omicron variant was first detected on November 24, 2021, in Southern Africa, it has now been detected in more than 110 countries and is estimated to continue to spread. Given the rapid spread and serious dangers of COVID-19, it is urgent to continuously improve and expand research on its clinical diagnosis and treatment. The analysis of this study identifies the laboratory results and clinical characteristics of probable Omicron. This study aimed to determine the laboratory results and clinical characteristics of probable Omicron patients at Dr. Wahidin Sudirohusodo Hospital. This descriptive study used a cross-sectional approach with medical record data of probable Omicron patients at Dr. Wahidin Sudirohusodo Hospital from January to July 2022 with a total of 241 research subjects. The results of the analysis showed that probable Omicron patients at Dr. Wahidin Sudirohusodo Hospital who were hospitalized consisted of 124 (51.5%) males and 117 (48.5%) females, 66 (22.8%) subjects with age range >60 years, 88 (30.4%) subjects with age range of 40-60 years, 45 (15.6%) subjects with age range 19-40 years and 42 (14.5%) subjects with age <18. Most subjects, which consisted of 79 (27.3%) patients reside in Makassar. The mean WBC count, NLR value, LMR value, and CT value found in this study were 10.8; 5.6; 0.5; and 33.94, respectively. The Omicron variant infects more males than females mainly at the age of 40-60 years, with a relatively low average CT value of 33.94 and a slight increase of NLR, MLR, and WBC count.

Downloads

Download data is not yet available.

References

Meo SA, Meo AS, Al-Jassir FF, Klonoff DC. Omicron SARS-CoV-2 new variant: Global prevalence and biological and clinical characteristics. Eur. Rev. Med. Pharmacol. Sci, 2021; 25: 8012–8018.

Wang X, Li X, Shang Yu, Wang J, Zhang X, et al. Ratios of neutrophil-to-lymphocyte and platelet-to-lymphocyte predict all-cause mortality in inpatients with Coronavirus Disease 2019 (COVID-19): A retrospective cohort study in a single medical center. Epidemiol. Infect, 2020; 148: e211.

Aleem A, Akbar Samad AB, Vaqar S. Emerging variants of SARS-CoV-2 and novel therapeutics against Coronavirus (COVID-19). 2023 May 1. Meo SA, Meo AS, Al-Jassir FF, Klonoff DC. Omicron SARS-CoV-2 new variant: Global prevalence and biological and clinical characteristics. Eur. Rev. Med. Pharmacol. Sci, 2021; 25: 8012–8018.

Wang X, Li X, Shang Yu, Wang J, Zhang X, et al. Ratios of neutrophil-to-lymphocyte and platelet-to-lymphocyte predict all-cause mortality in inpatients with Coronavirus Disease 2019 (COVID-19): A retrospective cohort study in a single medical center. Epidemiol. Infect, 2020; 148: e211.

Aleem A, Akbar Samad AB, Vaqar S. Emerging variants of SARS-CoV-2 and novel therapeutics against Coronavirus (COVID-19). 2023 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2023; PMID: 34033342.

Torjesen I. COVID-19: Omicron may be more transmissible than other variants and partly resistant to existing vaccines, scientists fear. BMJ 2021; 375: n2943.

Andriyoko B, Budiailmiawan L, Markus L. panduan interpretasi hasil pemeriksaan real time PCR S Gene Target Failure (SGTF) SARS-CoV-2 (PDS PatKLIn), 2022; 1: 69–71.

Ayanian S, Reyes J, Lynn L, Teufel K. The association between biomarkers and clinical outcomes in novel Coronavirus pneumonia in a US cohort. Biomark. Med, 2020; 14: 1091–1097.

Araf Y, Akter F, Tang YD, Fatemi R, Parvez MSA, et al. Omicron variant of SARS-CoV-2: Genomics, transmissibility, and responses to current COVID-19 vaccines. J Med Virol. 2022; 94(5): 1825-1832.

Huang H, Shan K, Liu J, Tao X, Periyasamy S. The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients. Bioorg. Chem, 2020; 103: 104230.

Ferré VM, Peiffer-Smadja N, Visseaux B, Descamps D, Ghosn J, Charpentier C. Omicron SARS-CoV-2 variant: What we know and what we don't. Anaesth Crit Care Pain Med, 2022; 41(1): 100998.

Brady E, Nielsen MW, Andersen JP, Oertelt-Prigione S. Lack of consideration of sex and gender in COVID-19 clinical studies. Nat. Commun, 2021; 12: 8–13.

Hu T, Zhang M, Deng A, Zhang Y, Li B, et al. Comparison of Omicron and Delta variant infection COVID-19 cases - Guangdong Province, China, 2022. China CDC Wkly, 2022; 4(18): 385-388.

Heo JY. Clinical and epidemiological characteristics of Coronavirus disease 2019 in the early stage of outbreak. Korean J. Med, 2020; 95: 1. Meo SA, Meo AS, Al-Jassir FF, Klonoff DC. Omicron SARS-CoV-2 new variant: Global prevalence and biological and clinical characteristics. Eur. Rev. Med. Pharmacol. Sci, 2021; 25: 8012–8018.