LEUKOSIT INFEKSI BAKTERI SISTEMIK

Abstract

Patients in intensive care unit (ICU) have a high risk for systemic bacterial infection. Serum procalcitonin (PCT) known as a marker
to predict bacterial infection, systemic inflammation responsse (SIRS) or sepsis. Another simple and easy indicator is by using leucocyte
count-differential count, absolute neutrophyl count (ANC), and immatur/total (I/T) neutrophyl ratio. The aim of this study was to
know the comparation of the leucocyte count-differential count, ANC, and I/T ratio with procalcitonin serum value in patients suspect
to systemic bacterial infection at ICU. A cross sectional study on 20 patients suspected with systemic bacterial infection in ICU. The data
was classified in 3 groups based on PCT serum value: group A (< 0.5 ng/mL), group B (0.5–2 ng/mL) and group C (> 2 ng/mL). The
data was analysed by one way ANOVA test if normally distributed, and by Kruskall-Wallis test if not normally distributed. Significancy
was confirmed at p < 0.05. A post hoc and Mann-Whitney test performed on a significant result. The frequency of group A was 3 (15%),
group B = 5 (25%), and group C = 12 (60%). There is no significant difference on leucocyte count in 3 groups (p = 0.953), neutrophyl
I/T ratio (p = 0.259), ANC (p = 0.91), eosinophyl count (p = 0.287), segment neutrophyl (p = 0.094), and monosit (p = 0.152).
There was a difference on lymphocyte count (p = 0.01) between group C with group A and group B and there was a difference on staff
neutrophyl count (p = 0.029) and total neutrophyl count (p = 0.003) between group A with group B and C (p = 0.029). In this study
were found differences on lymphocyte, staff neutrophyl and total neutropyl count to the PCT value